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Association Between Bundled Payment for Joint Replacement and Discharge to Institutional Postacute Care

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Question  What was the change in discharge to institutional postacute care after lower extremity joint replacement episodes among Medicare beneficiaries following implementation of the Comprehensive Care for Joint Replacement (CJR) bundled payments in 2016?

Findings  In this interim analysis of the first year of a 5-year randomized trial of 75 metropolitan statistical areas (MSAs) that were assigned the bundled payment model and 121 control MSAs that were not, the mean percentage of patient discharges to institutional postacute care was 33.7% in the control group and was 2.9 percentage points lower in MSAs covered by the CJR model, a significant difference.

Meaning  These interim findings suggest that CJR may reduce institutional postacute care following lower extremity joint replacement episodes among Medicare beneficiaries, although further evaluation is needed as the program is fully implemented over time.

Importance  Bundled payments are an increasingly common alternative payment model for Medicare, yet there is limited evidence regarding their effectiveness.

Objective  To report interim outcomes from the first year of implementation of a bundled payment model for lower extremity joint replacement (LEJR).

Design, Setting, and Participants  As part of a 5-year, mandatory-participation randomized trial by the Centers for Medicare & Medicaid Services, eligible metropolitan statistical areas (MSAs) were randomized to the Comprehensive Care for Joint Replacement (CJR) bundled payment model for LEJR episodes or to a control group. In the first performance year, hospitals received bonus payments if Medicare spending for LEJR episodes was below the target price and hospitals met quality standards. This interim analysis reports first-year data on LEJR episodes starting April 1, 2016, with data collection through December 31, 2016.

Exposure  Randomization of MSAs into the CJR bundled payment model group (75 assigned; 67 included) or to the control group without the CJR model (121 assigned; 121 included). Instrumental variable analysis was used to evaluate the relationship between inclusion of MSAs in the CJR model and outcomes.

Main Outcomes and Measures  The primary outcome was share of LEJR admissions discharged to institutional postacute care. Secondary outcomes included the number of days in institutional postacute care, discharges to other locations, Medicare spending during the episode (overall and for institutional postacute care), net Medicare spending during the episode, LEJR patient volume and patient case mix, and quality-of-care measures.

Results  Among the 196 MSAs and 1633 hospitals, 131 285 eligible LEJR procedures were performed during the study period (mean volume, 110 LEJR episodes per hospital) among 130 343 patients (mean age, 72.5 [SD, 0.91] years; 65% women; 90% white). The mean percentage of LEJR admissions discharged to institutional postacute care was 33.7% (SD, 11.2%) in the control group and was 2.9 percentage points lower (95% CI, −4.95 to −0.90 percentage points) in the CJR group. Mean Medicare spending for institutional postacute care per LEJR episode was $3871 (SD, $1394) in the control group and was $307 lower (95% CI, −$587 to −$27) in the CJR group. Mean overall Medicare spending per LEJR episode was $22 872 (SD, $3619) in the control group and was $453 lower (95% CI, −$909 to $3) in the CJR group, a statistically nonsignificant difference. None of the other secondary outcomes differed significantly between groups.

Conclusions and Relevance  In this interim analysis of the first year of the CJR bundled payment model for LEJR among Medicare beneficiaries, MSAs covered by CJR, compared with those that were not, had a significantly lower percentage of discharges to institutional postacute care but no significant difference in total Medicare spending per LEJR episode. Further evaluation is needed as the program is more fully implemented.

Trial Registration  ClinicalTrials.gov Identifier: NCT03407885; American Economic Association Registry Identifier: AEARCTR-0002521




Source: https://jamanetwork.com/journals/jama/article-abstract/2698927

Diet high in leucine may fuel breast cancer's drug resistance

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About one in eight women in the United States will develop breast cancer in her lifetime. The vast majority of these cancers rely on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone's effect on the tumor. However, many tumors eventually become resistant to tamoxifen, allowing cancer to recur or metastasize.

Now, a team of researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) has discovered an unexpected relationship between levels of the amino acid leucine and the development of tamoxifen resistance in ER+ breast cancer. Led by Senthil K. Muthuswamy, PhD, the researchers further identified a key protein that imports leucine into cells and modulates sensitivity to tamoxifen in ER+ cells in the lab setting. The findings, published today in the journal Nature, reveal a potential new strategy for overcoming resistance to endocrine drugs in ER+ breast cancer patients.

"Patients with ER+ breast cancer who develop endocrine-resistant and metastatic cancer have very poor life expectancy, usually less than five years survival, because they have limited treatment options available," said Muthuswamy, who is Director of the Cell Biology Program and Deputy Director of Translational Research in the Cancer Research Institute at BIDMC. "Our findings in the lab demonstrate that decreasing leucine levels suppresses proliferation of tumor cells, whereas increasing leucine enhances it. Furthermore, the findings open up the possibility that a low-leucine diet could be beneficial for patients with ER+ breast cancer."

Leucine is one of the 20 amino acids -- the building blocks of all proteins in our body -- and is among the 9 essential amino acids that must be obtained via food. Beef, chicken, pork and fish are all rich sources of leucine. Because cells can't produce leucine on their own, Muthuswamy and colleagues were able to test how manipulating levels of leucine in cells cultured in a dish would affect the growth of human derived ER+ breast cancer cells. The researchers reported that decreasing leucine levels suppressed ER+ breast cancer cells' division, while a tenfold increase of the amino acid enhanced it.

"Because animal proteins have higher amount of leucine compared to plant proteins, this study begins to identify a diet intervention strategy to help patients with ER+ breast cancers," said Muthuswamy. "Our research does not imply that animal proteins will enhance growth of breast cancer cells -- only that lowering leucine levels can be beneficial for patients diagnosed with ER+ breast cancer."

Surprisingly, the scientists also discovered that cells that were induced to become resistant to tamoxifen gained the ability to grow despite low levels of leucine. Further investigation revealed that a protein on the surface of cells, called SLC7A5, required for ferrying leucine into the cell, is present at higher levels in cells resistant to tamoxifen. Increasing the levels of SLC7A5 allows cells to absorb more leucine and was sufficient to make breast cancer cells resistant to tamoxifen and inhibiting SL7A5 using chemical inhibitor was sufficient to shrink ER+ tumors in mice. Muthuswamy believes inhibiting SLC7A5 could be a potential therapeutic approach in the treatment of ER+ breast cancers.

"Before this research, there was no reason to expect that estrogen biology has anything to do with affecting intracellular levels of leucine in cells," said first author, Yasuhiro Saito, PhD, a research fellow in the Department of Medicine and Pathology at BIDMC. "We have uncovered a new area of estrogen receptor biology, which will lead to new strategies to help patients with endocrine resistant breast cancer."

Even so, the discovery is in keeping with previous reports that decreasing overall leucine intake can lead to better metabolic health, Muthuswamy added. Decreasing the amount of total protein in the diet is known to improve metabolic health and longevity in rodent studies. Recent studies in human and mice demonstrated that that a low leucine diet can provide similar benefits. While protein restriction can make it difficult to meet daily nutrient requirements, a diet made-up of low- leucine plant proteins may be a better alternative for patients with ER+ breast cancer.

In follow up, Muthuswamy's team is investigating whether a leucine restricted diet can prevent growth or enhance response to therapy for ER+ breast cancer cells in mice.

"A properly controlled clinical study to assess clinical benefit of actively decreasing leucine intake in diet during treatment for ER+ breast cancer will be of significant value because a positive outcome can provide a simple intervention strategy that can help us better care for patients with endocrine-sensitive and resistant breast cancer," Muthuswamy said.

In addition to Muthuswamy and Saito, co-investigators include John M. Asara of BIDMC; Lewyn Li, Augustin Luna, Chris Sander and Myles Brown of Dana-Farber Cancer Institute; and Etienne Coyaud and Brian Raught of Princess Margaret Cancer Center and University of Toronto.

The work was supported by funding from the National Institutes of Health (NIH) (grant 5P01CA120964), a long term postdoctoral fellowship (LT000091/2014) from the Human Frontier Science Program and research funds from the Yamagata prefectural government and the City of Tsuruoka, and the Breast Cancer Research Foundation.



Source: https://www.sciencedaily.com/releases/2019/04/190417132750.htm

Anti-aging molecule NAD+ gets a boost from blocking an enzyme

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Nicotinamide adenine dinucleotide (NAD+) is a major player in nutrition today. Studies have shown that NAD+ concentrations decrease during aging and that recovering the body's levels of NAD+ can prolong both health span and even life span, making it the focus of much research in nutritional science, medicine, and even pharmaceutics.

In terms of biology, NAD+ is what is known as a "co-enzyme" -- a necessary molecule that helps an enzyme carry out its respective reaction in the cell. NAD+ is a common co-enzyme for multiple metabolic enzymes across all living cells, meaning that it is heavily involved in producing energy and keeping cells alive and healthy.

Publishing in Nature, scientists lead by Johan Auwerx at EPFL's Interfaculty Institute of Bioengineering in collaboration with TES Pharma have found a new way of increasing NAD+ in the kidney and liver by blocking an enzyme competing with its production.

The de novo synthesis of NAD+ in the cell begins with the amino acid tryptophan. One of the key enzymes involved in this process is ACMSD, which limits the amount of NAD+ produced by the de novo synthesis pathway.

The scientists were able to show that ACMSD controls the levels of NAD+ in the cell through a mechanism that doesn't seem to have changed during evolution: case-in-point, the researchers found that, in both the earthworm Caenorhabditis elegans and mice, blocking the enzyme resulted in higher NAD+ levels and enhanced mitochondrial function.

The inactivation of ACMSD also increased the activity of Sirtuin 1, an enzyme that NAD+ works with in its role as co-enzyme. Sirtuin 1 is known to play major roles in mitochondrial well-being, and as a result, the boost of NAD+ levels ultimately enhanced mitochondrial function.

The team then used two potent and selective inhibitors of ACMSD, developed by TES Pharma. "Since the enzyme is mostly found in the kidney and liver, we wanted to test the capacity of the ACMSD inhibitors to protect these organs from injury," explains Elena Katsyuba, first author of the paper.

Both inhibitors were shown to preserve kidney and liver function in animal models of acute kidney injury and of non-alcoholic fatty liver disease, offering much promise for their future therapeutic potential in humans. "The fact that ACMSD is exclusively present only in the liver and kidneys reduces the risk of negative repercussions of its loss on other organs," says Katsyuba. "Put simply, the enzyme will not be missed by an organ that does not have it anyway."

"Given the beneficial health effects of boosting NAD+ levels that we have seen in worm and mouse models of disease, we are looking forward to bringing these compounds soon to the clinic to the benefit of patients suffering from liver and kidney diseases, two areas with a large unmet clinical need," says Johan Auwerx.

Story Source:

Materials provided by Ecole Polytechnique Fédérale de Lausanne. Note: Content may be edited for style and length.



Source: https://www.sciencedaily.com/releases/2018/10/181024131258.htm

10 Stunning Serving Platters for Thanksgiving + The Holidays

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Let’s get one thing straight. The real star of Thanksgiving isn’t the food on the table — it’s what’s underneath it. For a style-conscious hostess, mediocre servewere just won’t do. This is especially true for Thanksgiving, where the food being served is the center of everyone’s attention.

We’ve got plenty of great ideas for making your tablescape or buffet space special, but all it really takes is a pretty platter or two. We’re sharing our dream lineup for Thanksgiving this year, from a chic platter to plate your bird to the cutest ceramic gravy vessel…
Enamel + Ash Cheese Dome |  The cute vintage feel of this enamelware dome is sure to add a splash of happy nostalgia to your table. Learn to make the ultimate cheese board here, then put it on display in style. CHECK OUT

 



Source: https://thechalkboardmag.com/serving-platters-for-thanksgiving

S2EP6: Chris Bell - MobilityWOD | Optimize Performance & Improve Mobility

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S2EP6: CHRIS BELL
Opioids + Kratom

A conversation about pain would not be complete without acknowledging opioids and all of the drugs used to treat pain. Chris Bell is the award winning documentary filmmaker behind Prescription Thugs (2015), that explores the opioid crisis in America. His newest film, A Leaf of Faith (2018), covers all aspects of the controversial drug, Kratom, a plant-based supplement showing big promise in pain relief. Chris has first-hand experience with chronic pain and the all to common drug abuse that comes with it. He talks openly about his experience with pain, drugs, death, and we go deep into all things Kratom. Chris joined us via Skype.

For more on Chris' movies check out his IMDb page!

Books, blogs, people and websites mentioned in the episode:




Source: https://www.mobilitywod.com/mwod_podcast/s2ep6-chris-bell/

What does nutrient density look like?

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Beyond all the words and numbers on Optimising Nutrition, it was great to see the food people created in response to the Nutrient Optimiser challenge when they focused on improving their micronutrient profile on the first Nutrient Optimiser Challenge.  

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People found that sharing their food photos with the Nutrient Optimiser Facebook Group was a great way to stay accountable and get feedback from people on the same journey.  It also inspired a lot of creativity.

It has also been a great way to build the database of nutrient dense meals and recipes in the Nutrient Optimiser that will help future users optimise their micronutrient profile.  

These nutrient-dense meals don’t fit neatly in a category.  Everyone used the tools in the Nutrient Optimiser to improve their nutrient density in their own way.   

As they say, a picture paints a thousand words, so here is a selection of some of the meals that people created when trying to improve the nutrient density of their diet as part of the challenge.  

Check out the Nutrient Optimiser Facebook Group for more photos and all the details of the recipes that sit behind these.   We’re hoping that the next Nutrient Density Challenge will produce even more fantastic food photos that show what highly nutritious and satiating food looks like.  

We’d love you to get on board and be a part of it this time around if you’re interested in optimising your food choices at a micronutrient level.  

But enough said. On to the photos.

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Race Recap: KLM Curaçao Half Marathon

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I have no problem with mapping out my own running route when I’m in a new city. After all, the best sightseeing is often done on foot, and when I can scratch my itch to be a total tourist and get in a run at the same, I’m all about it.

However, running around a strange city is even better when it’s done as part of a race. The logistics are covered, there’s hydration provided along the course, you often gain pedestrian access into areas you wouldn’t otherwise be able to run, and, of course, you’re out there with a whole community of other runners. It’s fun! It’s safe! And it’s awesome.

Last November, I had the opportunity to visit Curaçao — and participate in the KLM Curaçao Marathon — as a guest of the Curaçao Tourist Board. (Maybe you caught a bit of it in our Instagram Story.) In addition to the full marathon, there’s a half marathon, 10k, 5k, and a 9.7k trail run option, which was awesome because I was able to challenge myself with the half marathon distance, while my husband, Jared, stuck to the 10k.

As you might recall, the half marathon distance is a bit of a wild card for me — I’ve had disappointing races that I trained like crazy for, while others have ended in PRs that I had no right to expect. In this case, I didn’t have a ton of time to train up to the distance, but because the half marathon course for this particular race loops all through and around Willemstad (while the shorter distances are less exciting out-and-backs), I was determined to get through all 13.1 miles.

And now, I’m going to take you through the course with me! Because whether you’re trying to get through what feels like a never-ending winter or trying to find some inspiration to up your running game, you might want to consider booking a trip to Curaçao for this year’s race on November 24, 2019 — and I want you to know what you’re getting into!

(And, of course, there’s a lot more to Curaçao than just running. See what else I did on my weekend away — like swimming with sea turtles, practicing a little SUP yoga, and doing my share of fine dining — here!)

Race start: Jared and I stayed at the Hilton Curaçao, which is where the race starts, ends, and also where the post-race party takes place. I would definitely make the same choice again and encourage you to as well, because being able to wake up and walk straight down to the start line (not to mention being able to run upstairs for a quick rinse and change post-race) was incredible. This was even more helpful due to the fact that he and I were running different distances, which started an hour apart (start times are staggered by distance, ranging from 3:30 a.m. to 7:00 a.m. so that most runners finish within the same couple of hours or so).

Kilometers 1-6: The first hour was pretty dark (like, I could’ve used a headlamp on a few occasions. But even so, it was more hot and humid than I’d anticipated, which meant I was drenched with sweat by the time I hit the first notable landmark, the beautifully lit up Queen Emma floating pontoon bridge. I would be running over it later, but at this point, I simply ran by. Well, and stopped for a sweaty selfie, obviously.

3 predawn miles doesn’t usually equate to quite this much sweat.

Kilometers 7-9: Things got quite challenging as we made our way over the Queen Juliana Bridge, which is 185-feet high and generally only open to motor vehicles. The climb was intense, but the views were fantastic. The sun began to rise as I started my descent and I tried to take advantage of the free speed the downhill offered. I hadn’t gone in with a goal time, exactly, but my average pace was slower than I’d anticipated. Even as a Floridian, that heat and humidity hit me hard.

Kilometers 10-15: This stretch was a mostly straight out-and-back, which wasn’t as exciting as the first few kilometers, but it meant that I saw other runners going the opposite direction, which I always enjoy. Because it was along a straight road, I was able to zone out and settle into a pace pretty well, although I took full advantage of every water stop, dousing myself with a cup and filling my handheld water bottle with another.

Kilometer 16: I won’t lie — I was struggling a bit at this point, but I did my best to stick to the strongest pace I could because this was near the 10k turnaround, and I knew Jared was planning to wait for me there so we could run in together — and so he could snap a photo or two. (Yes, this meant that his finish time was … not great, but it was a very cool and unique option that we weren’t going to pass up!)

via GIPHY

Even if you don’t have someone waiting for you at this point, you’ll want to keep your eyes peeled for the big Curaçao sign at Queen Wilhelmina Park. If you’re one to take pictures during a race, this is a great photo opp. From here, we ran out over the floating bridge that I’d taken a selfie by earlier that morning. The sun was fully out now, and so the bridge lights had long since turned off, although it still offered a cool view of the colorful buildings and floating market as we made our way across.

Kilometers 17-end: This final section of the run takes you through the outdoor Renaissance Mall and Rif Fort, then goes largely along the waterfront, providing a tempting view of what awaits you at the beach just on the other side of the finish line.

Post-race party: Because we stayed at the race hotel, we not only had the opportunity to pop up to the room to shower and change, but we also made use of the daily breakfast buffet that was included with our package — and it’s worth shelling out for, let me tell you. Otherwise, there was some standard post-race fare available to runners (bananas, oranges), as well as food and beer available to purchase. This truly felt like a party due to the gorgeous setting, the crystal clear water, the lively music, and the happy chatter in a variety of languages (Dutch is common on this Dutch Caribbean island, but because Curaçao isn’t far from Venezuela, I also heard quite a bit of  Spanish, as well as Papiamento, a Spanish Creole language spoken on Curaçao, Aruba and Bonaire — and literally everyone I met also spoke excellent English).

A view of the post-race party from our balcony.

It’s worth noting that, while everyone receives a medal, awards do not go as deep as you might be used to in the States. The overall winners of each distance received awards — and most people seemed to stick around to cheer for them, which was pretty cool — but they weren’t handed out to the top three men and women in each age group. Great for those of us who aren’t placing anyway (because those ceremonies take forever), but I could see that being a disappointment if you’re hoping to hear your name called.

All in all, though, I really loved the race experience — almost as much as I loved the country of Curaçao itself. If you’re someone who likes tying a race into a vacation, this is one to keep in mind.

Are you also all about the race-cation? What’s your favorite — and what’s on your bucket list? —Kristen




Source: https://fitbottomedgirls.com/2019/03/race-recap-klm-curacao-half-marathon/

Where has The Savvy Celiac been?

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Where has The Savvy Celiac been?

January 24, 2017 by Amy Leger | G+ Amy Leger

Greetings from The Savvy Celiac.

It has been a crazy year and let’s face it, I have been off the grid a bit when it comes to The Savvy Celiac. My apologies.

Let me catch you up on where things stand and where they are going!

The Savvy Celiac update

As you know, we moved to Longmont, Colo. from Minnesota last spring and that changed everything. We had a new house, new schools for my teenage girls, new friends (or trying to make them), and a full-time job (for the first time since 2008) for me.  Needless to say the website suffered a bit.

I was able to get my bearings a little bit by the end of the summer and I made two other big changes.  I hired a personal trainer (and yes I’m down several inches and 10 pounds) and I also resigned as the Family Editor of Gluten-Free Living Magazine. With the magazine, it became too much to juggle with a new job. Plus, after five years, it felt like I had come full circle on all of the issues/subjects parents, families and children deal with when it comes to managing a gluten-free lifestyle. It was a very good run and I enjoyed every minute of it.

Emma's gluten-free ham, egg and cheese sandwich from Sun Rose

Emma’s gluten-free ham, egg and cheese sandwich from Sun Rose

Dining discoveries

That brings me to now. Life is finally starting to feel a bit more normal, like I’m in a groove. We have checked out a few places in Colorado that are gluten-free friendly:

  • T/ACO in Boulder –  street tacos and everything is gluten free because the soft taco shells used in the place are corn and same with the chips!
  • Sun Rose Cafe in Longmont – Emma had a great breakfast sandwich there using Glutino English Muffins
  • Amie’s Love a gluten-free bakery in Longmont – where I had the largest whoopie pie known to man!
That's a big whoopie pie from Amie's Love

That’s a big whoopie pie from Amie’s Love

My goal is to get back into the gluten-free community and share even more as Emma prepares to head off to college in the fall. Proud momma moment: she was accepted to Colorado Mesa University in Grand Junction to pursue nursing.

Thanks for your patience!

Tags: adventure, celiac, dining, food, free, gluten, gluten-free, move, relocate, transition, vacation




Source: http://www.thesavvyceliac.com/2017/01/24/where-has-the-savvy-celiac-been/

Gluten-Free Lemon Loaf Cake with Turmeric Collagen Drizzle

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Confession: this gluten-free lemon loaf cake didn’t last 24 hours in my kitchen.

Lemon loaf cake on a board sliced with drizzle in a bowl

If you’ve taken my wellness personality quiz (and if you haven’t, go do it!) then you know that I’ve often observed through my course clients that people approach health habits very differently.

I’m a Healthy Hedonist (duh), which means that restriction makes me feel anxious. I’m not an all or nothing kind of gal. Most of the time, I am pretty good at moderation. But the slippery slope of trying to swing both ways is that sometimes I end up sliding too far in one direction. And that is certainly the case whenever I bring baked goods into the house.

whole lemon loaf cake in a pan

Moderation is easier said than done, especially when indulgences involve addictive substances like sugar that can fuel cravings.

I can handle one piece of chocolate a night after dinner without a problem. But if there is a lemon loaf cake sitting on the counter, I am not able to have just one slice. Or just one half. Or if there are multiple, just one whole thing.

Perhaps this is due to my gluten-free scarcity mindset. Maybe it’s the blood sugar rollercoaster. Either way, it’s not a good scene, especially when I’m trying to ease into doing a mini vice detox with you in a few days!

whole lemon loaf cake drizzling lemon loaf cake

Since one of my tenets of healthy hedonism is to set yourself up for success at home so you can find more flexibility out in the world, that means I don’t bake very often. When I am eating sugar, I find my sweet fixes in other ways, like dark chocolate. Or I go out to a favorite bakery where I will have to spend $5 on a cookie, and therefore only purchase one.

But here’s the other thing: I love creating healthy gluten-free treats for you. Solution? When testing gluten-free lemon loaf cake recipes, I force the other half of my loaf upon my neighbor.

whole loaf of lemon cake on a counter

Force, you say? Who wouldn’t want the gift of a fresh, delicious baked good?

Well, a neighbor who has just told you that she is not eating carbs or sugar at the moment, and you insist that she accept the “gift” anyway. Sorry Christine!

You see, friends. Self-control can sometimes be selfish.

Luckily for us both though (because don’t you worry, I ate the other half by myself in one sitting), this lemon loaf cake is far less sinful than what I usually walk away with at my local bakery. It’s sweetened naturally with a modest amount of maple syrup and coconut sugar. It’s topped with a little anti-inflammatory turmeric coconut butter glaze–no powdered sugar here. And for a cake, it’s fairly high in protein thanks to the plentiful eggs, almond meal, and collagen powder, which boosts both the batter and the drizzle.

Lemon loaf cake on a board sliced

As I mentioned earlier this summer, I’ve been on a mission post-SIBO to get as much Great Lakes Gelatin Collagen as possible into my meals. Not only do my nails and hair feel stronger when I’m getting a regular dose, but it’s helping to rebuild my gut lining behind the scenes.

So in this case, I don’t feel so bad about having my lemon loaf cake, and making my neighbor eat half of it too.

Read on for the delicious, easy recipe for this gluten-free lemon cake. And if you lack both the will to moderate your portions and a neighbor to take some of them off your hands, rest assured that this loaf also freezes well!

With health and hedonism,

Phoebe

Lemon loaf cake on a board sliced with drizzle in a bowl

This lemon loaf cake recipe is made gluten-free with a mixture of AP gluten-free flour (I used Cup4Cup) and almond meal. The turmeric icing is adapted from the Sweet Laurel Cookbook from the donut chapter, with the addition of collagen for extra protein. You can omit if you’re vegetarian. One thing to note is that the collagen will make the batter extra giggly and dense – don’t sweat it. I promise it will turn out fluffy!

Instructions

  1. Make the cake: Preheat the oven to 350°. Grease and flour a 9-by-5-inch loaf pan or line with two piece of parchment paper. In a small mixing bowl, combine the flour, almond meal, baking powder, xanthan gum and poppy seeds. Whisk with a fork until well mixed.

  2. In a medium mixing bowl, stir together the olive oil, maple syrup, coconut sugar and vanilla. Add the eggs one at a time, mixing well between additions until smooth. Stir in the lemon zest and juice. Add the dry ingredients to the egg mixture in two additions, mixing until just combined. Stir in the Great Lakes Gelatin Collagen Hydrolysate.

  3. Transfer the batter to the prepared pan and bake in the middle of the oven until the top is golden brown and a toothpick inserted in the center comes out clean, about 50 minutes. Let the bread cool completely in the pan, then transfer it to a rack.

  4. Meanwhile, make the glaze: in a small saucepan over low heat, combine the coconut butter, lemon juice, maple syrup, vanilla, turmeric, water and Great Lakes Gelatin Collagen Hydrolysate. Whisk until smooth and silky.

  5. Drizzle the lemon loaf cake with the turmeric-lemon glaze and allow to set. Cut into slices and enjoy.

This gluten-free lemon loaf cake recipe is brought to you in partnership with my friends at Great Lakes Gelatin. All opinions are my own (obviously). Thank you for supporting the brands that make this site (and my gut healing) possible!




Source: https://feedmephoebe.com/gluten-free-lemon-loaf-cake-recipe/

Measles Cases Mount In Pacific Northwest Outbreak

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Source: https://choice.npr.org/index.html?origin=https://www.npr.org/sections/health-shots/2019/02/08/692665531/measles-cases-mount-in-pacific-northwest-outbreak

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